Review




Structured Review

Axion BioSystems maestro edge instrument
Maestro Edge Instrument, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/maestro+edge+system/maestro+edge+apparatus/pmc12277964-91-6-8
Average 90 stars, based on 1 article reviews
maestro edge instrument - by Bioz Stars, 2026-10
90/100 stars

Images

Related Articles

Microelectrode Array:

Article Title: Biosensing system for drug evaluation of amyotrophic lateral sclerosis based on muscle bundle and nano-biohybrid hydrogel composed of multiple motor neuron spheroids and carbon nanotubes
Article Snippet: Amyotrophic lateral sclerosis (ALS) results in muscle atrophy due to degeneration of the neuromuscular junctions (NMJs), the synapse responsible for the transmission of signals between motor neurons (MNs) and skeletal muscles.. Even though NMJ models have been developed, in vitro drug evaluation models for ALS disease are still lacking due to the absence of a sensing system and immature NMJs in a model system.. Moreover, a threedimensional (3D) biosensing system that can observe drug-induced muscle recovery and movement still does not exist.

Article Title: Glioblastoma remodelling of human neural circuits decreases survival.
Article Snippet: The coverslips were rinsed three times in PBS and then mounted with VECTA antifade mounting medium with DAPI (Vector Laboratories). .. Spontaneous extracellular neuronal recordings were carried out using the Maestro Edge system with an integrated heating system and temperature controller (Axion Biosystems) in combination with the Axion 24-well CytoView MEA plates (each well housing a 4 × 4 16-channel electrode array that are 350 μm away from each other) and Axion Integrated Studio (AxIS) Navigator (v.3.5.2; Axion Biosystems). .. Images were captured at 1,024 × 1,024 resolution using a ×10 objective on the Nikon C2 confocal microscope.

Article Title: Glioma-neuronal circuit remodeling induces regional immunosuppression
Article Snippet: .. Briefly, we used Axion 24-well CytoView MEA plates, each well of which contains a 4×4 16 channel electrode array with channels spaced 350 μm apart, and the Maestro Edge system with integrated heating system and temperature controller (Axion Biosystems). ..

Article Title: Nanoscale Diesel-Exhaust Particulate Matter (DPM) Impairs Synaptic Plasticity of Human iPSCs-Derived Cerebral Organoids
Article Snippet: Nanoscale diesel-exhaust particulate matter (DPM), a cause of air pollution, has recently become the subject of many studies because it affects human health and causes neural diseases.. However, most studies are based on epidemiology, cell, sliced tissue or animal models, and the toxic effects of nanoscale DPM on inducing disease in living human brain remain unclear.. In this study, we developed a new in vitro model to investigate the synaptic plasticity impairment of human brain affected by nanoscale DPM using cerebral organoid (CO) mimicking human brain.

Activity Assay:

Article Title: FMRP Controls Neuronal Architecture and Synaptic Content of NMDA Receptors in Cultured Hippocampal Neurons.
Article Snippet: .. Spontaneous electrical activity of neurons was recorded using Maestro Edge system (Axion BioSystems) with AxIS Navigator software (Axion BioSystems). .. Recordings were carried out in NBM-A (GIBCO) supplemented with 0.12 mg/ml gentamicin (GIBCO), 2% B27 (GIBCO) and 0.5 mM l-glutamine.

Article Title: In vivo assessment of iPSC-cardiomyocyte loaded auxetic cardiac patches following chronic myocardial infarction.
Article Snippet: Novel cardiac patch designs achieved by advanced 3D manufacturing continue to have favorable impacts on the repair and regeneration of the myocardium after injury.. Briefly, auxetic units with a negative Poisson’s ratio have already shown remarkable promise for serving as a next-generation complex scaffold in left ventricular disease.. In this study we biofabricated a 3D printed polycaprolactone (PCL) cardiac auxetic patch loaded with high density contractile induced pluripotent stem cell-derived cardiomyocytes (iCMs) and examined the synergist effect of iCM auxetic patches on a chronic myocardial infarct rodent model compared to a stiffer non-auxetic control patch architecture.

Software:

Article Title: FMRP Controls Neuronal Architecture and Synaptic Content of NMDA Receptors in Cultured Hippocampal Neurons.
Article Snippet: .. Spontaneous electrical activity of neurons was recorded using Maestro Edge system (Axion BioSystems) with AxIS Navigator software (Axion BioSystems). .. Recordings were carried out in NBM-A (GIBCO) supplemented with 0.12 mg/ml gentamicin (GIBCO), 2% B27 (GIBCO) and 0.5 mM l-glutamine.

Article Title: In vivo assessment of iPSC-cardiomyocyte loaded auxetic cardiac patches following chronic myocardial infarction.
Article Snippet: Novel cardiac patch designs achieved by advanced 3D manufacturing continue to have favorable impacts on the repair and regeneration of the myocardium after injury.. Briefly, auxetic units with a negative Poisson’s ratio have already shown remarkable promise for serving as a next-generation complex scaffold in left ventricular disease.. In this study we biofabricated a 3D printed polycaprolactone (PCL) cardiac auxetic patch loaded with high density contractile induced pluripotent stem cell-derived cardiomyocytes (iCMs) and examined the synergist effect of iCM auxetic patches on a chronic myocardial infarct rodent model compared to a stiffer non-auxetic control patch architecture.

other:

Article Title: Topical administration of novel FKBP12 ligand MP-004 improves retinal function and structure in retinitis pigmentosa models
Article Snippet: Cell cytolysis was evaluated by impedance measurement (1 min intervals, 10 kHz) using the Maestro Edge system (Axion Biosystems).



Similar Products

90
Axion BioSystems maestro edge instrument
Maestro Edge Instrument, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/maestro+edge+system/maestro+edge+apparatus/pmc12277964-91-6-8
Average 90 stars, based on 1 article reviews
maestro edge instrument - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Axion BioSystems mea maestro edge system
Mea Maestro Edge System, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/maestro+edge+system/maestro+edge+mea+system/10__3390_slash_receptors4030012-65-19-28
Average 90 stars, based on 1 article reviews
mea maestro edge system - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Axion BioSystems maestro edge
Maestro Edge, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/maestro+edge+system/maestro+edge/pm40540154-103-22-24
Average 90 stars, based on 1 article reviews
maestro edge - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Axion BioSystems maestro edge system
Maestro Edge System, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/maestro+edge+system/maestro+edge/pm40408975-82-13-15
Average 90 stars, based on 1 article reviews
maestro edge system - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Axion BioSystems mea system maestro edge
Restoration of synchrony loss in primary neurons from αSyn transgenic mice upon SNX5 knockdown. a Experimental timeline of primary neuron <t>isolation,</t> <t>maturation</t> and siPOOL application in vitro; DIV, days in vitro. b Quantification of SNX5 mRNA expression in primary neurons from the transgenic Thy1-αSyn (Line 61) mouse model. The cells were transfected with siPOOL siRNAs against SNX5 or a negative control siRNA, or untransfected. c Multiwell microelectrode array <t>(MEA)</t> measurement of neuronal synchrony at 18 h after application of DMSO (left side bars) or 50 µmol/L bafilomycin A1 in DMSO of the same conditions as described in panel b . The graph shows results from 1 out of 3 representative technical replicates; bars represent mean ± SEM; n.s. = not significant, * P < 0.05; Two-way ANOVA with Sidak’s post-hoc test
Mea System Maestro Edge, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/maestro+edge+system/maestro+edge+mea+system/pmc12131658-123-7-11
Average 90 stars, based on 1 article reviews
mea system maestro edge - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Axion BioSystems maestro edge mea platform
Restoration of synchrony loss in primary neurons from αSyn transgenic mice upon SNX5 knockdown. a Experimental timeline of primary neuron <t>isolation,</t> <t>maturation</t> and siPOOL application in vitro; DIV, days in vitro. b Quantification of SNX5 mRNA expression in primary neurons from the transgenic Thy1-αSyn (Line 61) mouse model. The cells were transfected with siPOOL siRNAs against SNX5 or a negative control siRNA, or untransfected. c Multiwell microelectrode array <t>(MEA)</t> measurement of neuronal synchrony at 18 h after application of DMSO (left side bars) or 50 µmol/L bafilomycin A1 in DMSO of the same conditions as described in panel b . The graph shows results from 1 out of 3 representative technical replicates; bars represent mean ± SEM; n.s. = not significant, * P < 0.05; Two-way ANOVA with Sidak’s post-hoc test
Maestro Edge Mea Platform, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/maestro+edge+system/maestro+edge/pmc12084003-289-5-9
Average 90 stars, based on 1 article reviews
maestro edge mea platform - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Axion BioSystems axion maestro edge
Restoration of synchrony loss in primary neurons from αSyn transgenic mice upon SNX5 knockdown. a Experimental timeline of primary neuron <t>isolation,</t> <t>maturation</t> and siPOOL application in vitro; DIV, days in vitro. b Quantification of SNX5 mRNA expression in primary neurons from the transgenic Thy1-αSyn (Line 61) mouse model. The cells were transfected with siPOOL siRNAs against SNX5 or a negative control siRNA, or untransfected. c Multiwell microelectrode array <t>(MEA)</t> measurement of neuronal synchrony at 18 h after application of DMSO (left side bars) or 50 µmol/L bafilomycin A1 in DMSO of the same conditions as described in panel b . The graph shows results from 1 out of 3 representative technical replicates; bars represent mean ± SEM; n.s. = not significant, * P < 0.05; Two-way ANOVA with Sidak’s post-hoc test
Axion Maestro Edge, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/maestro+edge+system/axion+biosystems+maestro+mea/pm40373045-210-12-16
Average 90 stars, based on 1 article reviews
axion maestro edge - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Axion BioSystems axion maestro edge machine
Restoration of synchrony loss in primary neurons from αSyn transgenic mice upon SNX5 knockdown. a Experimental timeline of primary neuron <t>isolation,</t> <t>maturation</t> and siPOOL application in vitro; DIV, days in vitro. b Quantification of SNX5 mRNA expression in primary neurons from the transgenic Thy1-αSyn (Line 61) mouse model. The cells were transfected with siPOOL siRNAs against SNX5 or a negative control siRNA, or untransfected. c Multiwell microelectrode array <t>(MEA)</t> measurement of neuronal synchrony at 18 h after application of DMSO (left side bars) or 50 µmol/L bafilomycin A1 in DMSO of the same conditions as described in panel b . The graph shows results from 1 out of 3 representative technical replicates; bars represent mean ± SEM; n.s. = not significant, * P < 0.05; Two-way ANOVA with Sidak’s post-hoc test
Axion Maestro Edge Machine, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/maestro+edge+system/axion+maestro+edge+machine/pmc12220938-198-14-18
Average 90 stars, based on 1 article reviews
axion maestro edge machine - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

Image Search Results


Restoration of synchrony loss in primary neurons from αSyn transgenic mice upon SNX5 knockdown. a Experimental timeline of primary neuron isolation, maturation and siPOOL application in vitro; DIV, days in vitro. b Quantification of SNX5 mRNA expression in primary neurons from the transgenic Thy1-αSyn (Line 61) mouse model. The cells were transfected with siPOOL siRNAs against SNX5 or a negative control siRNA, or untransfected. c Multiwell microelectrode array (MEA) measurement of neuronal synchrony at 18 h after application of DMSO (left side bars) or 50 µmol/L bafilomycin A1 in DMSO of the same conditions as described in panel b . The graph shows results from 1 out of 3 representative technical replicates; bars represent mean ± SEM; n.s. = not significant, * P < 0.05; Two-way ANOVA with Sidak’s post-hoc test

Journal: Translational Neurodegeneration

Article Title: A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson’s disease cell model

doi: 10.1186/s40035-025-00486-5

Figure Lengend Snippet: Restoration of synchrony loss in primary neurons from αSyn transgenic mice upon SNX5 knockdown. a Experimental timeline of primary neuron isolation, maturation and siPOOL application in vitro; DIV, days in vitro. b Quantification of SNX5 mRNA expression in primary neurons from the transgenic Thy1-αSyn (Line 61) mouse model. The cells were transfected with siPOOL siRNAs against SNX5 or a negative control siRNA, or untransfected. c Multiwell microelectrode array (MEA) measurement of neuronal synchrony at 18 h after application of DMSO (left side bars) or 50 µmol/L bafilomycin A1 in DMSO of the same conditions as described in panel b . The graph shows results from 1 out of 3 representative technical replicates; bars represent mean ± SEM; n.s. = not significant, * P < 0.05; Two-way ANOVA with Sidak’s post-hoc test

Article Snippet: The plates were transferred daily into the Maestro Edge MEA system (Axion Biosystems) for evaluation of cellular functions during maturation.

Techniques: Transgenic Assay, Knockdown, Isolation, In Vitro, Expressing, Transfection, Negative Control, Microelectrode Array